Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease
نویسندگان
چکیده
منابع مشابه
intravenous immunoglobulin resistant kawasaki disease
abstract kawasaki disease is a systemic vasculitis that mainly affects younger children. although the definite cause still remains unknown but the clinical and epidemiologic findings discuss an infectious cause. the prevalence of incomplete kawasaki disease reported 15 to 36.2%, and it is more frequent in the extremes of the age spectrum. non delayed treatment of disease should be initiated bec...
متن کاملUse of Corticosteroid in Children with Unresponsiveness to Intravenous Immunoglobulin in Kawasaki Disease
Background Kawasaki Disease (KD) is a vasculitis with multi-organ involvementof unknown etiology; it is the most common cause of pediatric-heart diseases in developed countries. Treatment with Intravenous Immunoglobulin (IVIG) prevents coronary artery lesions; although there are some IVIG-resistant cases, combination therapy with corticosteroids and IVIG is one of the recommendations for treatm...
متن کاملPredictors of Intravenous Immunoglobulin (IVIG) Resistance in Children with Kawasaki Disease in Calabria Region, Italy
Background Kawasaki disease (KD) is the second most common childhood vasculitis and one of the main causes of acquired heart disease in children. Recent work focuses on the early diagnostic importance of those risk factors that indicate resistance to intravenous immunoglobulin (IVIG) treatment. The objectives of this study were to identify clinical, laboratory and/or instrumental factors that c...
متن کاملPredictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease
PURPOSE It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD. METHODS We examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between...
متن کاملRecurrent Kawasaki disease resistant to initial treatment with intravenous immunoglobulin.
Kawasaki disease (mucocutaneous lymph node syndrome) is a disease of unknown etiology characterized by vasculitis which may affect the coronary arteries. Young children are most commonly affected although the disease has been described in adults. Kawasaki disease (KD) was first described by Dr Tomisaku Kawasaki in 1967. Since then, more cases have been reported worldwide, the majority being fro...
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ژورنال
عنوان ژورنال: Journal of Microbiology, Immunology and Infection
سال: 2016
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2014.11.001